Skip to main content
Department of Obstetrics, Gynecology & Reproductive Sciences OB/GYN
  1. Department of OBGYN & Reproductive Sciences
  2. Research
  3. Research Labs
  4. Tan Lab
  5. Publications

Tan Lab Publications

View all Publications in PubMed

Featured Publications

Faculty Member (2023–present)
#Co-corresponding author

4)  Tan K#, Higgins K, Liu Q, Wilkinson MF#. An ancient enhancer rapidly evolving in the human lineage promotes neural development and cognitive flexibility. Sci Adv. 2025 Aug 15;11(33):eadt0534. doi: 10.1126/sciadv.adt0534.

3)  Tan K#, Wilkinson MF#. Biological roles of nonsense-mediated RNA decay: insights from the nervous system. Curr Opin Genet Dev. 2025 May 22;93:102356. doi: 10.1016/j.gde.2025.102356. 

2)  Tan K#, Sebat J, Wilkinson MF#. Cell type- and factor-specific nonsense-mediated RNA decay. Nucleic Acids Res. 2025 May 10;53(9). doi: 10.1093/nar/gkaf395. 

1)  Tan K, Wilkinson MF. A translation regulator that drives spermatogonial stem cell formation. Andrology. 2024 Oct 9;. doi: 10.1111/andr.13780. 

 

Postdoctoral Research (2016–2023)
*Co-first author; #Co-corresponding author

12)  Tan K, Wilkinson MF. Developmental regulators moonlighting as transposons defense factors. Andrology. 2023 Jul;11(5):891-903. doi: 10.1111/andr.13427. 

11)  Tan K, Stupack DG, Wilkinson MF. Nonsense-mediated RNA decay: an emerging modulator of malignancy. Nat Rev Cancer. 2022 Aug;22(8):437-451. doi: 10.1038/s41568-022-00481-2. 

10)  Tan K#, Wilkinson MF#. Regulation of both transcription and RNA turnover contribute to germline specification. Nucleic Acids Res. 2022 Jul 22;50(13):7310-7325. doi: 10.1093/nar/gkac542. 

9)  Tan K, Song HW, Wilkinson MF. RHOX10 drives mouse spermatogonial stem cell establishment through a transcription factor signaling cascade. Cell Rep. 2021 Jul 20;36(3):109423. doi: 10.1016/j.celrep.2021.109423. 

8)  Tan K, Kim ME, Song HW, Skarbrevik D, Babajanian E, Bedrosian TA, Gage FH, Wilkinson MF. The Rhox gene cluster suppresses germline LINE1 transposition. Proc Natl Acad Sci U S A. 2021 Jun 8;118(23). doi: 10.1073/pnas.2024785118. 

7)  Tan K, Wilkinson MF. A single-cell view of spermatogonial stem cells. Curr Opin Cell Biol. 2020 Dec;67:71-78. doi: 10.1016/j.ceb.2020.07.005.  

6)  Tan K, Jones SH, Lake BB, Chousal JN, Shum EY, Zhang L, Chen S, Sohni A, Pandya S, Gallo RL, Zhang K, Cook-Andersen H, Wilkinson MF. The role of the NMD factor UPF3B in olfactory sensory neurons. Elife. 2020 Aug 10;9. doi: 10.7554/eLife.57525. 

5)  Tan K, Song HW, Thompson M, Munyoki S, Sukhwani M, Hsieh TC, Orwig KE, Wilkinson MF. Transcriptome profiling reveals signaling conditions dictating human spermatogonia fate in vitro. Proc Natl Acad Sci U S A. 2020 Jul 28;117(30):17832-17841. doi: 10.1073/pnas.2000362117. 

4)  Tan K, Song HW, Wilkinson MF. Single-cell RNAseq analysis of testicular germ and somatic cell development during the perinatal period. Development. 2020 Feb 3;147(3). doi: 10.1242/dev.183251. 

3)  Tan K, Wilkinson MF. Human Spermatogonial Stem Cells Scrutinized under the Single-Cell Magnifying Glass. Cell Stem Cell. 2019 Feb 7;24(2):201-203. doi: 10.1016/j.stem.2019.01.010. 

2)  Sohni A*, Tan K*, Song HW*, Burow D, de Rooij DG, Laurent L, Hsieh TC, Rabah R, Hammoud SS, Vicini E, Wilkinson MF. The Neonatal and Adult Human Testis Defined at the Single-Cell Level. Cell Rep. 2019 Feb 5;26(6):1501-1517.e4. doi: 10.1016/j.celrep.2019.01.045. 

1)  Ramaiah M*, Tan K*, Plank TM, Song HW, Chousal JN, Jones S, Shum EY, Sheridan SD, Peterson KJ, Gromoll J, Haggarty SJ, Cook-Andersen H, Wilkinson MF. A microRNA cluster in the Fragile-X region expressed during spermatogenesis targets FMR1. EMBO Rep. 2019 Feb;20(2). doi: 10.15252/embr.201846566. 

 

Predoctoral Research (2010–2016)

5)  Tan K, Wang X, Zhang Z, Miao K, Yu Y, An L, Tian J. Downregulation of miR-199a-5p Disrupts the Developmental Potential of In Vitro-Fertilized Mouse Blastocysts. Biol Reprod. 2016 Sep;95(3):54. doi: 10.1095/biolreprod.116.141051. 

4)  Tan K, Zhang Z, Miao K, Yu Y, Sui L, Tian J, An L. Dynamic integrated analysis of DNA methylation and gene expression profiles in in vivo and in vitro fertilized mouse post-implantation extraembryonic and placental tissues. Mol Hum Reprod. 2016 Jul;22(7):485-98. doi: 10.1093/molehr/gaw028. 

3)  Tan K, Wang Z, Zhang Z, An L, Tian J. IVF affects embryonic development in a sex-biased manner in mice. Reproduction. 2016 Apr;151(4):443-53. doi: 10.1530/REP-15-0588. 

2)  Tan K, An L, Miao K, Ren L, Hou Z, Tao L, Zhang Z, Wang X, Xia W, Liu J, Wang Z, Xi G, Gao S, Sui L, Zhu DS, Wang S, Wu Z, Bach I, Chen DB, Tian J. Impaired imprinted X chromosome inactivation is responsible for the skewed sex ratio following in vitro fertilization. Proc Natl Acad Sci U S A. 2016 Mar 22;113(12):3197-202. doi: 10.1073/pnas.1523538113. 

1)  Tan K, An L, Wang SM, Wang XD, Zhang ZN, Miao K, Sui LL, He SZ, Nie JZ, Wu ZH, Tian JH. Actin Disorganization Plays a Vital Role in Impaired Embryonic Development of In Vitro-Produced Mouse Preimplantation Embryos. PLoS One. 2015;10(6):e0130382. doi: 10.1371/journal.pone.0130382.