Ongoing Projects
Ongoing projects in the lab include:
- biomarker discovery for prediction and diagnosis of pregnancy complications;
- identification and validation of key regulators of human placental development;
- modeling human pancreatic and hepatic development, both in vitro by directed differentiation of pluripotent stem cells and in silico using gene regulatory networks;
- genomic and epigenomic characterization of different substates of pluripotency
Ongoing Clinical Research Projects
We also have a number of ongoing clinical research projects, including studying:
- the clinical and psychological impacts of using next-generation sequencing for prenatal genetic diagnosis of babies with major birth defects
- the physical and psychological effects of bedrest compared to moderate physical activity in pregnancies complicated by preterm premature rupture of membranes