Research

Ongoing Projects

Ongoing projects in the lab include:

• biomarker discovery for prediction and diagnosis of pregnancy complications;
• identification and validation of key regulators of human placental development;
• modeling human pancreatic and hepatic development, both in vitro by directed differentiation of pluripotent stem cells and in silico using gene regulatory networks;
• genomic and epigenomic characterization of different substates of pluripotency

Ongoing Clinical Research Projects

We also have a number of ongoing clinical research projects, including studying:

• the clinical and psychological impacts of using next-generation sequencing for prenatal genetic diagnosis of babies with major birth defects
• the physical and psychological effects of bedrest compared to moderate physical activity in pregnancies complicated by preterm premature rupture of membranes